In-Office Retail Products

Certified CBD topicals for your practice and retail shelf. No minimum orders.

3 products
Pro Cream
3.4 fl oz (100mL) Airless Pump Bottle

Pro Cream

Muscle, Joint, Foot & Leg

CBD Cooling Cream
3.4 fl oz (100mL) Airless Pump Bottle

CBD Cooling Cream

Full Spectrum Relief & Recovery

Pro Roll-On
Roller Bottle | 3.04 oz (90mL)

Pro Roll-On

Quick Recovery: Muscle, Back & Joint

No minimum orders · Available in 6 or 12-packs

Why Practitioners Choose Kannaco

Professional Grade. Not Marketing Grade.

Every product in this collection is formulated to meet the standards practitioners demand — not the minimums the market accepts.

100%

Full Transparency

Every batch is independently tested. COAs are available on every product page — potency, purity, and contaminant panels included.

ISO-accredited third-party labs

LegitScript Certified

Kannaco holds LegitScript certification — the highest compliance standard in the CBD industry, required by Google, Facebook, and major payment processors.

Verified compliant merchant

Practitioner Support

Our clinical team provides dosing guidance, patient education materials, and ongoing support so you can recommend with confidence.

Dedicated practitioner success team

Ready to stock Certified CBD?

Apply for wholesale access in under 2 minutes.

Practitioner FAQ

Everything Practitioners Ask Before Ordering

Here are the most common questions from licensed practitioners.

Still have questions?

Contact Kannaco Wholesale

Research & Evidence

The Science Behind the Endocannabinoid System

ECS research spans more than three decades and thousands of peer-reviewed studies. Here are the key milestones that shaped our understanding of this remarkable system — and why it matters for your wellness today.

1988

First Cannabinoid Receptor Discovered

Dr. Allyn Howlett and William Devane identified the first cannabinoid receptor (CB1) in the rat brain, establishing the biological basis for how cannabinoids affect the nervous system.

Source: Howlett et al., Molecular Pharmacology, 1988
1992

Anandamide — The Body's Own Cannabinoid

Researchers at Hebrew University discovered anandamide, the first endocannabinoid — a naturally occurring compound produced by the human body that binds to the same receptors as THC.

Source: Devane et al., Science, 1992
1993

CB2 Receptor Identified

The second major cannabinoid receptor, CB2, was discovered in the immune system. This finding revealed that the ECS plays a significant role in immune regulation and peripheral tissue response.

Source: Munro et al., Nature, 1993
1995

2-AG: The Most Abundant Endocannabinoid

2-arachidonoylglycerol (2-AG) was identified as the most abundant endocannabinoid in the body, with full agonist activity at both CB1 and CB2 receptors — playing a key role in immune and neurological regulation.

Source: Mechoulam et al., Biochemical Pharmacology, 1995
1998

Raphael Mechoulam Names the ECS

The Israeli chemist who first isolated THC in 1964 formally characterized the endocannabinoid system as a unified regulatory network, coining the term and establishing its role in maintaining homeostasis.

Source: Mechoulam & Ben-Shabat, European Journal of Biochemistry, 1999
2003

U.S. Government Patents Cannabinoids as Neuroprotectants

The U.S. Department of Health and Human Services was granted Patent #6,630,507 for cannabinoids as antioxidants and neuroprotectants, acknowledging their therapeutic potential.

Source: U.S. Patent 6,630,507, 2003
2009

ECS Receptors Found in Human Skin

Researchers confirmed the presence of both CB1 and CB2 receptors throughout human skin — in keratinocytes, hair follicles, sebaceous glands, and sensory nerve fibers — validating the mechanism for topical cannabinoid activity.

Source: Bíró et al., Trends in Pharmacological Sciences, 2009
2014

Clinical Endocannabinoid Deficiency Recognized

Dr. Ethan Russo proposed and documented Clinical Endocannabinoid Deficiency (CECD) as a condition where insufficient ECS tone may contribute to chronic discomfort, sleep disruption, and mood challenges.

Source: Russo, Cannabis and Cannabinoid Research, 2016
35+
Years of Peer-Reviewed ECS Research
20,000+
Published Studies on Cannabinoids
100+
Known Phytocannabinoids in Hemp
2
Primary ECS Receptor Types Identified